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Christos Tikellis Selected Research

alagebrium

8/2012Alagebrium reduces glomerular fibrogenesis and inflammation beyond preventing RAGE activation in diabetic apolipoprotein E knockout mice.
8/2008Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.
4/2003A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes.

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Christos Tikellis Research Topics

Disease

7Inflammation (Inflammations)
01/2019 - 03/2005
5Diabetic Nephropathies (Diabetic Nephropathy)
01/2018 - 03/2003
4Atherosclerosis
11/2020 - 11/2007
3Diabetes Mellitus
11/2020 - 11/2012
3Hypertrophy
03/2015 - 10/2005
2Hyperglycemia
11/2020 - 05/2009
2Cardiovascular Diseases (Cardiovascular Disease)
11/2020 - 01/2018
2Diabetes Complications
12/2018 - 03/2003
2Albuminuria
01/2018 - 07/2002
2Cardiomegaly (Heart Hypertrophy)
08/2008 - 02/2005
2Hypertension (High Blood Pressure)
04/2008 - 03/2005
2Insulin Resistance
11/2007 - 03/2005
1Prediabetic State (Prediabetes)
11/2020
1Vascular Diseases (Vascular Disease)
01/2018
1Metabolic Syndrome (Dysmetabolic Syndrome X)
08/2014
1Necrosis
11/2012
1Fibrosis (Cirrhosis)
03/2005
1Hypoxia (Hypoxemia)
02/2005
1Infarction (Infarctions)
02/2005
1Type 2 Diabetes Mellitus (MODY)
04/2004
1Heart Diseases (Heart Disease)
04/2003
1Amyloid Plaque
03/2003
1Experimental Diabetes Mellitus
03/2003

Drug/Important Bio-Agent (IBA)

4Apolipoproteins E (ApoE)IBA
01/2019 - 11/2007
3AngiotensinsIBA
01/2019 - 03/2003
3alagebriumIBA
08/2012 - 04/2003
3Angiotensin IIIBA
04/2008 - 04/2004
2Glucose (Dextrose)FDA LinkGeneric
11/2020 - 03/2005
2LigandsIBA
01/2019 - 11/2012
2Peptides (Polypeptides)IBA
01/2019 - 03/2003
2lipoxin A4IBA
12/2018 - 01/2018
2Streptozocin (Streptozotocin)FDA Link
12/2018 - 01/2018
2LipoxinsIBA
12/2018 - 01/2018
2LipidsIBA
01/2018 - 08/2008
2Insulin (Novolin)FDA Link
03/2015 - 03/2005
2EnzymesIBA
05/2009 - 03/2003
2Angiotensin-Converting Enzyme 2IBA
04/2008 - 03/2003
2Proteins (Proteins, Gene)FDA Link
09/2006 - 03/2003
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2005 - 02/2005
1Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
11/2020
1CholesterolIBA
11/2020
1Receptor for Advanced Glycation End ProductsIBA
11/2020
1Platelet-Derived Growth FactorIBA
12/2018
1perindopril drug combination indapamideIBA
01/2018
1Biomarkers (Surrogate Marker)IBA
01/2018
1Gliclazide (Diamicron)IBA
01/2018
18-Hydroxy-2'-DeoxyguanosineIBA
01/2018
1CollagenIBA
01/2018
1PerindoprilFDA LinkGeneric
03/2015
1OsteoprotegerinIBA
08/2014
1TNF-Related Apoptosis-Inducing LigandIBA
11/2012
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
08/2012
1Advanced Glycation End ProductsIBA
08/2012
1ApolipoproteinsIBA
08/2012
1Lysine (L-Lysine)FDA Link
05/2009
1Histone MethyltransferasesIBA
05/2009
1ChromatinIBA
05/2009
1Histone DemethylasesIBA
05/2009
1ChloridesIBA
08/2008
1Superoxides (Superoxide)IBA
08/2008
1Type 2 Angiotensin ReceptorIBA
04/2008
1Prorenin ReceptorIBA
04/2008
1Peroxisome Proliferator-Activated Receptors (PPAR)IBA
11/2007
1PPAR alphaIBA
11/2007
1LDL CholesterolIBA
11/2007
1Advanced Oxidation Protein Products (AOPP)IBA
10/2005
1Valsartan (Vals)FDA Link
10/2005
1PyridoxamineIBA
10/2005
1SaltsIBA
10/2005
1Angiotensin Receptor AntagonistsIBA
03/2005
1Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
03/2005
1angiotensin I (1-9)IBA
02/2005
1Messenger RNA (mRNA)IBA
02/2005
1Ramipril (Altace)FDA LinkGeneric
02/2005
1Islet Amyloid PolypeptideIBA
03/2003
1Biological ProductsIBA
03/2003
1nephrinIBA
07/2002

Therapy/Procedure

1Therapeutics
01/2018
1Intraperitoneal Injections
01/2018
1Glycemic Control
05/2009